News

Long confined to the injectable route, research peptides are arriving in oral format. BPC-157, semaglutide, KPV, SLU-PP-332: what the oral route changes for laboratory handling, and the limits to know.

BPC-157 and TB-500 (Thymosin β-4) dominate research on tissue repair. Mechanisms, targets, studies, protocols and the BPC + TB stack synergy: the complete 2025 research guide.

Tesamorelin, CJC-1295, Sermorelin, Ipamorelin, GHRP-6, Hexarelin: two families, two mechanisms, one GH/IGF-1 axis. The complete guide to choosing and combining in research settings.

Mono, dual, or triple agonist? Head-to-head breakdown of the three peptides dominating post-2023 metabolic research — mechanisms, pivotal NEJM trials, clinical differentiation. Summary table and expert FAQ.

Decode complete peptide characterization: preparative and analytical RP-HPLC, high-resolution LC-MS Orbitrap/QTOF, 2D NMR (COSY/TOCSY/NOESY), Edman degradation, MS/MS peptide mapping, circular dichroism. The 10 techniques that separate a research-grade peptide from a dubious one, with detection limits and QC strategy.

Master the mechanisms that destroy your peptides: Met oxidation, Asn deamidation, hydrolysis, aggregation. Lyophilization protocols, storage conditions, optimal reconstitution and shelf-life QC. The technical pillar every laboratory must integrate to guarantee peptide integrity in exploratory research.

Merrifield principle, Fmoc and Boc strategies, resins (Wang, Rink amide, 2-chlorotrityl), coupling reagents (HBTU, HATU, DIC/HOBt), synthesis cycle, TFA cleavage, RP-HPLC purification, LC-MS and Kaiser test quality control. The scientific reference on synthetic peptide manufacturing.

Melanocortin system, MC1R to MC5R receptors, pan-agonist (Melanotan II) and MC4R-selective (PT-141 bremelanotide, afamelanotide Scenesse) mechanisms, pharmacokinetics, research-only reconstitution protocols, stability, safety signals (pigmentation, sexual function, nausea). The scientific reference.

Structure, amylin mechanism, CTR + RAMP1/2/3 receptor, pharmacokinetics, REDEFINE program (CagriSema), comparison versus pramlintide Symlin, GLP-1 synergy, research-only reconstitution protocols, stability and outlook. The scientific reference on cagrilintide.

Structure, triple agonist mechanism, pharmacokinetics, TRIUMPH program (1-4, Obesity, HFpEF, MASH), comparison versus semaglutide and tirzepatide, research-only reconstitution protocols, stability and regulatory outlook. The scientific reference on retatrutide.

Comprehensive scientific overview of growth hormone secretagogues: GHRH analogues (sermorelin, CJC-1295, tesamorelin), peptide GHRPs (Ipamorelin, GHRP-2/6, hexarelin), non-peptide GHS-R1a agonist (MK-677). Pharmacology, GHRH+GHRP synergy, rodent models, analytical QC, RUO framework.

Technical dossier on tirzepatide for research use: hybrid GIP-GLP-1 structure, dual GLP-1R/GIPR activation, pharmacokinetics, incretin synergy, DIO and ZDF models, QC analytics. Strictly RUO use.

Scientific synthesis on research dermatological peptides: GHK-Cu and copper complexes, Matrixyl and synthetic tripeptides, Argireline and acetylhexapeptides, collagen mechanisms and in vitro studies. Strict RUO framework.

Scientific overview of cognitive peptides in preclinical research: Semax (ACTH4-10), Selank (tuftsin), Dihexa (angiotensin IV), BDNF/NGF mechanisms and rodent behavioural models. Strict RUO framework, no human use.

Reference dossier on semaglutide for research use: molecular structure, GLP-1R mechanism, extended half-life, preclinical models, QC analytics and reconstitution best practices. Mandatory RUO reminder.

TB-500 is a synthetic thymosin β-4 fragment widely studied for its effects on angiogenesis, cell migration and wound healing. Comprehensive guide: structure, mechanisms, experimental models, pharmacokinetics and research protocols.

DSIP, orexin, galanin, MCH: mapping of neuromodulator peptides explored in research on sleep-wake cycles, circadian regulation and NREM/REM architectures.

Epithalon, humanin, FOXO4-DRI, MOTS-c: overview of peptides explored in research on cellular senescence, telomere maintenance and mitochondrial pathways involved in aging.

Couriers, lead times, cold chain, intra-EU and extra-EU customs, RUO traceability: everything labs need to know to receive their research peptides in full compliance.

Long R3 IGF-1: modified variant, reduced IGFBP affinity, extraordinary half-life. Scientific decoding of the most studied peptide in RUO anabolic research.

Regulation, quality, cost, traceability, legal uses: the two worlds have nothing in common. Understand the boundary before diving in.

HPLC, mass, sterility test, crude vs net purity: master every line of a COA to sort serious suppliers from opaque vendors.

Composition, role of benzyl alcohol, differences with sterile water and water for injection, storage, laboratory use. The reference guide to cleanly reconstitute a peptide.

Lyophilized powder or reconstituted solution: temperatures, duration, containers, freeze-thaw cycles, degradation signs. All laboratory-validated storage reflexes to preserve purity and activity.

Comprehensive scientific overview of the GLP-1 revolution in research: molecular mechanisms of incretins, evolution of mono/bi/tri-agonist analogues, experimental protocols and research directions.

Legal framework, molecule families, supplier selection criteria, receipt, storage, reconstitution: everything a researcher must master to acquire research peptides in France in 2026, in strict compliance with RUO regulation and customs requirements.

Comprehensive scientific guide on BPC-157 in preclinical research: gastric origin, molecular mechanisms, animal studies, methodological controversies and RUO protocols.

HPLC purity, molecular mass, peptide content... How to interpret CoA data to assess the quality of your peptides.

Eli Lilly announces early results for 2025. This new peptide has shown up to 24% weight loss in phase 2, surpassing all existing treatments.

According to Grand View Research, the therapeutic peptide sector is growing at 9.8% annually. The reasons behind this surge.

Researchers at UT Southwestern have identified the neurons targeted by semaglutide. A major breakthrough in understanding these medications.

Certain peptides are banned in competition by the World Anti-Doping Agency. An overview of 2024 regulations and the substances involved.

Peptide stability depends on proper handling. Our recommendations to preserve the integrity of your research compounds.

In 2023, the FDA classified BPC-157 as Category 2. What this decision means for researchers, suppliers, and users.

A randomized double-blind clinical trial confirms improved skin hydration and wrinkle reduction with collagen peptides.

The sale of peptides for research purposes is strictly regulated in the EU. What you need to know before placing an order.

Collagen stimulation, wound healing, antioxidant properties: why this peptide has become essential in premium cosmetic formulations.

With over $20 billion in sales in 2024, semaglutide illustrates the medical and commercial potential of therapeutic peptides.

36 studies analyzed from 1993 to 2024. Researchers take stock of what science really knows about injectable peptides.

A randomized controlled study shows that 15g of collagen peptides per day reduce muscle stress markers after exercise.

These two peptides activate complementary biological pathways. A 2025 systematic review examines the preclinical studies.

BPC-157 has intrigued the scientific community for over 30 years. A look back at Prof. Sikiric's work and the current state of research.